Lipid-based delivery systems have emerged as powerful tools in pharmaceutical research due to their ability to address the solubility and bioavailability challenges of poorly water-soluble drugs. Their versatility enables the encapsulation of both hydrophilic and hydrophobic molecules, while their superior biocompatibility ensures safe and controlled drug delivery.
Lipid-based delivery systems are utilized across various administration routes, including oral, ocular, intranasal, dermal, transdermal, parenteral, and vaginal. These systems can efficiently integrate with the lipid matrix of the skin, enhancing permeability and making them ideal for transdermal drug delivery. In addition, they safeguard encapsulated molecules from enzymatic or chemical degradation, allowing controlled release and improved therapeutic outcomes. With surface modifications, such as PEGylation or antibody conjugation, lipid-based systems can achieve targeted delivery, making them highly functionalized drug carriers.